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Investigation into conolidine has triggered discovery of the opioid receptor in the body named ACKR3/CXCR7. ACKR3 is apparently one of the most popular target for conolidine, which also disregards the other 4 classical opioid receptors(3).Conolidine has become present in the tabernaemontana divaricata plant, that is within the Apocynaceae relative
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